Atypical pneumonia makes up a significant proportion of community-acquired pneumonia. Mycoplasma pneumoniae is a common cause of community-acquired pneumonia (CAP), and the disease usually has a prolonged, gradual onset. Structural lung disease with abnormal lung parenchyma affects the pattern of infiltrates. [Medline]. Atypical presentation of Legionella pneumonia among patients with underlying cancer: A fifteen-year review. Chest radiograph shows dense consolidation in both lower lobes. Neumayr L, Lennette E, Kelly D, Earles A, Embury S, Groncy P, et al. [Full Text]. [10], (Scans of atypical bacterial pneumonia are depicted below.). All material on this website is protected by copyright, Copyright © 1994-2021 by WebMD LLC. 133(6):1124-5. Intense and diffuse lung uptake of 99mTc-MDP in a patient with pneumonia associated with secondary hemophagocytic lymphohistiocytosis. 65 (11):1837-1842. [Medline]. J Exp Med. 2017 Mar. Lee H, Yun KW, Lee HJ, Choi EH. [Medline]. A sensitive and rapid immunoassay for Mycoplasma pneumoniae in children with pneumonia based on single-walled carbon nanotubes. The next stage is referred to as red hepatization. 2010 Jun. Its clinical presentation … 1980 Apr. Matsubara K, Morozumi M, Okada T, Matsushima T, Komiyama O, Shoji M, et al. [Medline]. Eugene C Lin, MD is a member of the following medical societies: American College of Nuclear Medicine, American College of Radiology, Radiological Society of North America, Society of Nuclear Medicine and Molecular ImagingDisclosure: Nothing to disclose. Kawai Y, Miyashita N, Kubo M, et al. [3] First thought to be a virus, Eaton's agent was proved to be a Mycoplasma species in 1961. 2015 Aug. 57 (4):773-5. [Medline]. [Medline]. Di Marco E, Cangemi G, Filippetti M, Melioli G, Biassoni R. Development and clinical validation of a real-time PCR using a uni-molecular Scorpion-based probe for the detection of Mycoplasma pneumoniae in clinical isolates. Shakeel Amanullah, MD is a member of the following medical societies: American College of Chest PhysiciansDisclosure: Nothing to disclose. No visible dental staining in children treated with doxycycline for suspected Rocky Mountain Spotted Fever. J Chin Med Assoc. 112(1 Pt 1):87-95. 1938. Michael Joseph Bono, MD, FACEP is a member of the following medical societies: Alpha Omega Alpha, American College of Emergency Physicians, Medical Society of Virginia, Society for Academic Emergency MedicineDisclosure: Nothing to disclose. 2012 May. 111:2377-84. Genotyping and macrolide resistance of Mycoplasma pneumoniae identified in children with community-acquired pneumonia in Medellín, Colombia. 2000 Jan. 174(1):37-41. In 1944, Eaton was credited with discovering a specific agent, coined Eaton's agent, as the principal cause of primary atypical pneumonia. Mycoplasma pneumoniae (see mycoplasma pneumonia) is the causative organism in up to 20% of community acquired pneumonia and is often seen in pediatric populations and young adults 3. ), The infiltrates in Mycoplasma pneumonia can be unilateral, multilobar, or bilateral. Harrison's Principles of Internal Medicine. Underlying parenchymal lung abnormalities usually predispose patients to pneumonia. Hong Kong Med J. Legionella pneumophila infection presenting as headache, confusion and dysarthria in a human immunodeficiency virus-1 (HIV-1) positive patient: case report. Schulze M, Vogel W, Spira D, Sauter A, Hetzel J, Horger M. Reduced perfusion in pulmonary infiltrates of high-risk hematologic patients is a possible discriminator of pulmonary angioinvasive mycosis: a pilot volume perfusion computed tomography (VPCT) study. Mycoplasma pneumonia is usually mild and results in a rapid resolution of any radiologic findings. However, it tends to be more severe in patients with sickle cell anemia. Ultrasonography can help differentiate between consolidation and effusion. Mina Farhad, MD, PhD is a member of the following medical societies: Radiological Society of North AmericaDisclosure: Nothing to disclose. Permanent residual fibrosis is observed in as many as 25% of patients. The classic etiologic agents of atypical pneumonia are Legionella species, Mycoplasma pneumoniae, and Chlamydia pneumoniae. PURPOSE OF REVIEW: We present the key advances in the infections that clinicians conventionally associate with atypical pneumonia: legionellosis, Mycoplasma pneumonia, Chlamydophila species pneumonia … Constitutional symptoms often predominate over respiratory findings. Biosci Trends. [Medline]. Mustafa MI, Al-Marzooq F, How SH, Kuan YC, Ng TH. Rahimian M, HosseiniB M. Serological study of Bordetella Pertussis, Mycoplasma Pneumonia and Chlamydia Pneumonia in Iranian hajj pilgrims with prolonged cough illnesses: A follow-up study. In 1938, Reimann described the first cases of mycoplasmal pneumonia in man and coined the term "primary atypical pneumonia" after observing 7 patients in Philadelphia with marked constitutional symptoms, upper and lower respiratory tract symptoms, and a protracted course with gradual resolution. 2003 Jun. J Pediatr. Radiologic resolution of Legionella pneumonia may take 6-12 months. Mellick LB, Verma N. The Mycoplasma pneumoniae and bullous myringitis myth. ), Mild Legionella pneumonia may manifest with bilateral involvement of the lung parenchyma. Diseases & Conditions, You are being redirected to Background. 2016 Jan. 72 (1):45-51. Llibre JM, Urban A, Garcia E, Carrasco MA, Murcia C. Bronchiolitis obliterans organizing pneumonia associated with acute Mycoplasma pneumoniae infection. Atypical pneumonia, also known as walking pneumonia, is any type of pneumonia not caused by one of the pathogens most commonly associated with the disease. J Infect. A 38-year-old patient with Mycoplasma pneumonia. 2004 May. Sharma L, Losier A, Tolbert T, Dela Cruz CS, Marion CR. 2010 Dec. 11(6):849-51. Clin Infect Dis. Azumagawa K, Kambara Y, Murata T, Tamai H. Four cases of arthritis associated with Mycoplasma pneumoniae infection. Mycoplasma pneumonia-associated acute hepatitis in an adult patient without lung infection. Chest CT findings and clinical features in mild Legionella pneumonia. Although in most cases presentation can be in the milder spectrum of community-acquired pneumonia… [Medline]. 2008 Feb. 46(2):727-31. rate Their meta-analysis of 12 studies with 1515 patients found the sensitivity and specificity to be 0.88 (95% CI: 0.86–0.90) and 0.86 (95% CI: 0.83–0.88), respectively. [Medline]. (Mycoplasma pneumonia is shown in the image below. 2000 Apr. The incubation of mycoplasmal pneumonia tends to be smoldering and averages a period of 2-3 weeks, in contrast to that of influenza and other viral pneumonias, which generally average a few days. Kamizono S, Ohya H, Higuchi S, Okazaki N, Narita M. Three familial cases of drug-resistant Mycoplasma pneumoniae infection. 2007 Oct. 30(4):415-21. [Medline]. 2009 Apr. Paul Blackburn, DO, FACOEP, FACEP is a member of the following medical societies: American College of Emergency Physicians, Arizona Medical Association, American College of Osteopathic Emergency Physicians, American Medical AssociationDisclosure: Nothing to disclose. Pediatr Emerg Care. Mina Farhad, MD, PhD Clinical Instructor of Radiology, New York University School of Medicine; Head of Thoracic Imaging, Department of Radiology, Lenox Hill Hospital [14] Stevens-Johnson syndrome, Overview Diagnosis and Tests Management and Treatment Prevention Outlook / Prognosis. 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